Search Results - stefan+radtke

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Selection and Use of Hematopoietic Stem Cells for Cell Transplantation and Gene Therapy Approaches Defined population predicts and quantitatively correlates with <em>in vivo</em> engraftment and multilineage potential. Hematopoietic stem cells (HSC) are the preferred target population for <em>ex vivo</em> gene therapy...

Published: 8/28/2024 | Updated: 8/28/2024 | Inventor(s): Stefan Radtke, HanS-Peter Kiem, Kurt Berckmueller, Roland Strong, Peter Rupert

Keywords(s): HSC Therapy, Lentiviral, Small Molecule, Target, Vectors

Category(s): Research Tool, Gene Therapy

Human and Nonhuman Primate Hematopoietic Stem/Repopulating Cells and Methods for Enriching The Same

Published: 4/16/2025 | Updated: 8/28/2024 | Inventor(s): HanS-Peter Kiem, Jennifer Adair, Stefan Radtke

Keywords(s): HSC Therapy

Category(s): Cell Therapy, Gene Therapy

Luteinizing hormone as a means of promoting HSC expansion ex vivo

Methods to Target Hematopoietic Stem Cells for Ablation or Expansion Luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists to target and expand HSCs. Hematopoietic stem cell transplant (HCT) has been curative for many cancer malignancies and monogenetic diseases. However, current clinical limitations include...

Published: 2/4/2025 | Updated: 10/4/2017 | Inventor(s): Jarrod Dudakov, Marcel Van Den Brink, Enrico Velardi, HanS-Peter Kiem, Stefan Radtke, Scott James

Keywords(s): Assay / Method, HSC Therapy

Category(s): Cell Therapy, Research Tool, Therapeutic