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Targeted delivery into CD90+ cells
Selection and Use of Hematopoietic Stem Cells for Cell Transplantation and Gene Therapy Approaches Defined population predicts and quantitatively correlates with <em>in vivo</em> engraftment and multilineage potential. Hematopoietic stem cells (HSC) are the preferred target population for <em>ex vivo</em> gene therapy...
Published: 8/28/2024
|
Updated: 8/28/2024
|
Inventor(s):
Stefan Radtke
,
HanS-Peter Kiem
,
Kurt Berckmueller
,
Roland Strong
,
Peter Rupert
Keywords(s):
HSC Therapy
,
Lentiviral
,
Small Molecule
,
Target
,
Vectors
Category(s):
Research Tool
,
Gene Therapy
Multimeric NKG2D for immunomodulation
NKG2D Biologic to Reduce Immune Cell Activation A multimeric decoy to block activation of NKG2D and treat autoimmune and inflammatory diseases, and for use in vaccine development. Dr. Roland Strong and Dr. Martin Prlic have developed a multimeric NKG2D decoy that will bind all NKG2D ligands and block the NKG2D pathway. NKG2D is a receptor...
Published: 12/27/2023
|
Updated: 10/21/2019
|
Inventor(s):
Roland Strong
,
Martin Prlic
,
Mesfin Gewe
,
Thomas Spies
,
Veronika Groh-Spies
,
Peter Rupert
Keywords(s):
Protein / Peptide
Category(s):
Therapeutic
,
Vaccine
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