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Assay relating to COVID-19
Neutalizing Monoclonal Antibodies Against SARS-CoV-2 for COVID-19 Screening and Treatment Development of neutralizing monoclonal antibodies (mAbs) that bind to the spike glycoprotein on SARS-CoV-2.The WHO declared COVID-19 a global pandemic as of March, 2020. The infection is caused by SARS-CoV-2, a beta coronavirus with 79.5% genome sequence identify...
Published: 4/18/2025
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Updated: 12/3/2020
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Inventor(s):
Leonidas Stamatatos
,
Andrew Mcguire
,
Marie Pancera
Keywords(s):
Protein / Peptide
Category(s):
Therapeutic
Methods for HIV vaccination
Two-Step Immunization Strategy to Elicit HIV Neutralizing Antibodies Two-step immunization process guiding the maturation of VRC01-like antibodies by accommodating a conserved position of Env, which is known to restrict CD4-binding sites. VRC01-class antibodies are considered potent and broad neutralizing antibodies (bnAbs) for HIV-1 and...
Published: 5/15/2025
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Updated: 12/3/2020
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Inventor(s):
Leonidas Stamatatos
,
Andrew Mcguire
,
Katherine Parks
Keywords(s):
Protein / Peptide
Category(s):
Vaccine
Multimerized HIV gp120s
Multimerized HIV gp120s for Vaccine Development An engineered HIV Env glycoprotein that improves antibody-recognition potential for HIV vaccine development. Dr. Leo Stamatatos and Dr. Roland Strong have developed a unique and promising approach to developing an effective HIV vaccine by engineering an HIV Env glycoprotein using specific...
Published: 5/15/2025
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Updated: 5/17/2017
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Inventor(s):
Roland Strong
,
Colin Correnti
,
Leonidas Stamatatos
,
Andrew Mcguire
Keywords(s):
Protein / Peptide
Category(s):
Therapeutic
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