Search Results - andrew+mcguire

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Neutalizing Monoclonal Antibodies Against SARS-CoV-2 for COVID-19 Screening and Treatment Development of neutralizing monoclonal antibodies (mAbs) that bind to the spike glycoprotein on SARS-CoV-2.The WHO declared COVID-19 a global pandemic as of March, 2020. The infection is caused by SARS-CoV-2, a beta coronavirus with 79.5% genome sequence identify...

Published: 4/18/2025 | Updated: 12/3/2020 | Inventor(s): Leonidas Stamatatos, Andrew Mcguire, Marie Pancera

Keywords(s): Protein / Peptide

Category(s): Therapeutic

Methods for HIV vaccination

Two-Step Immunization Strategy to Elicit HIV Neutralizing Antibodies Two-step immunization process guiding the maturation of VRC01-like antibodies by accommodating a conserved position of Env, which is known to restrict CD4-binding sites. VRC01-class antibodies are considered potent and broad neutralizing antibodies (bnAbs) for HIV-1 and...

Published: 5/15/2025 | Updated: 12/3/2020 | Inventor(s): Leonidas Stamatatos, Andrew Mcguire, Katherine Parks

Keywords(s): Protein / Peptide

Category(s): Vaccine

EBV antibodies

EBV Neutralizing Antibody and Vulnerability Site for Vaccine Design A human monoclonal antibody that neutralizes EBV infections in both B cells and epithelial cells, and new approaches to developing an EBV vaccine. Dr. McGuire and colleagues have isolated a human monoclonal antibody that binds the gH/gL protein on Epstein-Barr virus (EBV)....

Published: 2/4/2025 | Updated: 7/2/2018 | Inventor(s): Andrew Mcguire

Keywords(s): Hybridoma / Antibody

Category(s): Therapeutic, Vaccine

Multimerized HIV gp120s

Multimerized HIV gp120s for Vaccine Development An engineered HIV Env glycoprotein that improves antibody-recognition potential for HIV vaccine development. Dr. Leo Stamatatos and Dr. Roland Strong have developed a unique and promising approach to developing an effective HIV vaccine by engineering an HIV Env glycoprotein using specific...

Published: 5/15/2025 | Updated: 5/17/2017 | Inventor(s): Roland Strong, Colin Correnti, Leonidas Stamatatos, Andrew Mcguire

Keywords(s): Protein / Peptide

Category(s): Therapeutic