Search Results - andrew+mcguire

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Neutralizing monoclonal antibodies against the KSHV gH/gL protein

Neutralizing Antibodies Against Kaposi’s Sarcoma-Associated Herpesvirus A set of human-derived neutralizing antibodies against KSHV derived from KSHV-infected donors. <p>Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) is an oncogenic human gamma herpesvirus responsible for Kaposi’s sarcoma (KS) and several rare but severe...

Published: 1/9/2026 | Inventor(s): Andrew Mcguire, Jim Boonyaratanakornkit, Warren Phipps, Marie Pancera

Keywords(s): Hybridoma / Antibody

Category(s): Therapeutic

Assay relating to COVID-19

Neutalizing Monoclonal Antibodies Against SARS-CoV-2 for COVID-19 Screening and Treatment Development of neutralizing monoclonal antibodies (mAbs) that bind to the spike glycoprotein on SARS-CoV-2.The WHO declared COVID-19 a global pandemic as of March, 2020. The infection is caused by SARS-CoV-2, a beta coronavirus with 79.5% genome sequence identify...

Published: 1/5/2026 | Inventor(s): Leonidas Stamatatos, Andrew Mcguire, Marie Pancera

Keywords(s): Protein / Peptide

Category(s): Therapeutic

Methods for HIV vaccination

Two-Step Immunization Strategy to Elicit HIV Neutralizing Antibodies Two-step immunization process guiding the maturation of VRC01-like antibodies by accommodating a conserved position of Env, which is known to restrict CD4-binding sites. VRC01-class antibodies are considered potent and broad neutralizing antibodies (bnAbs) for HIV-1 and...

Published: 5/15/2025 | Inventor(s): Leonidas Stamatatos, Andrew Mcguire, Katherine Parks

Keywords(s): Protein / Peptide

Category(s): Vaccine

Multimerized HIV gp120s

Multimerized HIV gp120s for Vaccine Development An engineered HIV Env glycoprotein that improves antibody-recognition potential for HIV vaccine development. Dr. Leo Stamatatos and Dr. Roland Strong have developed a unique and promising approach to developing an effective HIV vaccine by engineering an HIV Env glycoprotein using specific...

Published: 7/8/2025 | Inventor(s): Roland Strong, Colin Correnti, Leonidas Stamatatos, Andrew Mcguire

Keywords(s): Protein / Peptide

Category(s): Therapeutic