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Accurate Modeling of Clinical Trials to Guide Antiviral Development

Accurate Modeling of Clinical Trials to Guide Antiviral Development A mathematical framework to optimize antiviral drug selection, dosing, and clinical trial design. While notable for enormous successes, clinical development of antiviral therapies lacks efficiency. The most salient example is the discovery and deployment of safe and effective...

Published: 7/22/2025 | Updated: 7/22/2025 | Inventor(s): Joshua Schiffer

Keywords(s): Bioinformatics, IT / Software

Category(s): Health IT

Widely encoded colorectal cancer-associated bacterial genes in human microbiomes

Bacterial gene-associated methods and compositions for diagnosing and treating colorectal cancer The present disclosure provides compositions and non-invasive methods for diagnosing a subject at risk for developing, or having, or at risk for progressing on colorectal cancer (CRC) based on analysis of bacterial species in the gut microbiome of the...

Published: 6/12/2024 | Updated: 6/12/2024 | Inventor(s): Neelendu Dey, Samuel Minot

Keywords(s): Bioinformatics, Biomarker, Microbiome, Protein / Peptide

Category(s): Diagnostic

Optimized assay and efficient computational workflow to deliver same-day leukemia diagnostics

Long Range Sequencing for the Detection of Fusion Genes A CRISPR-Cas9 enrichment Nanopore sequencing assay for long-read sequencing. Fusion genes occur in 30% of AML patients, resulting in distinct types of AML. Identification of these structural variants help in diagnostic classification and drive targeted therapies. Recognition of fusion variants...

Published: 7/8/2025 | Updated: 12/6/2023 | Inventor(s): Cecilia Yeung, Olga Sala-Torra

Keywords(s): Bioinformatics, Nucleic Acid

Category(s): Diagnostic