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Accurate Modeling of Clinical Trials to Guide Antiviral Development

Accurate Modeling of Clinical Trials to Guide Antiviral Development A mathematical framework to optimize antiviral drug selection, dosing, and clinical trial design. <p>While notable for enormous successes, clinical development of antiviral therapies lacks efficiency. The most salient example is the discovery and deployment of safe and...

Published: 8/5/2025 | Updated: 7/22/2025 | Inventor(s): Joshua Schiffer

Keywords(s): Bioinformatics, IT / Software

Category(s): Health IT

Widely encoded colorectal cancer-associated bacterial genes in human microbiomes

Bacterial gene-associated methods and compositions for diagnosing and treating colorectal cancer The present disclosure provides compositions and non-invasive methods for diagnosing a subject at risk for developing, or having, or at risk for progressing on colorectal cancer (CRC) based on analysis of bacterial species in the gut microbiome of the...

Published: 6/12/2024 | Updated: 6/12/2024 | Inventor(s): Neelendu Dey, Samuel Minot

Keywords(s): Bioinformatics, Biomarker, Microbiome, Protein / Peptide

Category(s): Diagnostic

Optimized assay and efficient computational workflow to deliver same-day leukemia diagnostics

Long Range Sequencing for the Detection of Fusion Genes A CRISPR-Cas9 enrichment Nanopore sequencing assay for long-read sequencing. Fusion genes occur in 30% of AML patients, resulting in distinct types of AML. Identification of these structural variants help in diagnostic classification and drive targeted therapies. Recognition of fusion variants...

Published: 7/8/2025 | Updated: 12/6/2023 | Inventor(s): Cecilia Yeung, Olga Sala-Torra

Keywords(s): Bioinformatics, Nucleic Acid

Category(s): Diagnostic