Search Results - jason+bielas

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Quantitative method for accurately counting DTCs, CTCs, and ctDNA in a biological sample – or any cell “tagged” with DNA insert

Barcoding for the Tracking and Quantification of DNASystem and methods for digital quantification and tracking of cells and DNA including, DTC, CTCs, and ctDNA.Dr. Bielas and colleagues have been working on developing methods to quantify DNA and reduce background noise to better track, sequence, and quantify DNA. Genetic constructs are created using...

Published: 7/14/2023 | Updated: 10/4/2019 | Inventor(s): Jason Bielas

Keywords(s): Assay / Method, Nucleic Acid

Category(s): Research Tool, Therapeutic, Diagnostic

Digital quantification of random mitochondrial DNA deletions

Digital Deletion Detection and QuantiSize This method allows for measurement of rare deletions, while concurrently gathering information about size and homogeneity of the unknown template. Dr. Bielas has developed a sensitive, quantitative method to detect rare mutations in genomic and mitochondrial DNA. The main strategy is a three-step...

Published: 4/18/2025 | Updated: 2/8/2018 | Inventor(s): Jason Bielas, Sean Taylor, Matthew Laurie

Keywords(s): Assay / Method, Nucleic Acid

Category(s): Diagnostic, Research Tool