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NOD2 acts as a master regulator of regeneration pathways in the thymus

NOD2 Mediated Thymic Regeneration Boosts Compromised Immune Function Promotion of thymic regeneration through reduction or inhibition of nucleotide-binding oligomerization domain-containing protein 2 (NOD2) by upregulating regenerative molecules (e.g., interleukin (IL)-22, IL-23, and bone morphogenetic protein 4 (BMP4)). As the primary...

Published: 2/4/2025 | Updated: 10/4/2019 | Inventor(s): Jarrod Dudakov, Sinéad Kinsella

Keywords(s): Target

Category(s): Therapeutic