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Chimeric antigen receptor designs for improved recognition of low-density antigens

CAR Design Improvements for the Recognition of Low-Density Antigens Methods and tools to increase CAR-T cell recognition of tumor cells expressing low density antigens Adoptive transfer of CAR-expressing T cells is an effective cancer therapy for a proportion of individuals with B cell malignancies and multiple myeloma, but efficacy is limited...

Published: 8/28/2024 | Updated: 5/21/2020 | Inventor(s): Alexander Salter, Stanley Riddell, Anusha Rajan

Keywords(s): Immuno Oncology

Category(s): Cell Therapy